C188

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C188

Sigma

 

6-Hydroxychlorzoxazone

solid

Synonym:5-Chloro-6-hydroxy-2(3H)-benzoxazolone, 5-Chloro-6-hydroxybenzoxazone
CAS Number:1750-45-4
Linear Formula:C7H4ClNO3
Molecular Weight:185.56
MDL number:MFCD00143502

Description

ApplicationCYP2E1 & 1A2 metabolite of chlorzoxazone.

Properties

formsolid
solubilityH2O:  insoluble
 ethanol:  moderately soluble

Safety

Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Gloves
Hazard CodesXi
Risk Statements36/37/38
Safety Statements26
WGK Germany2
RTECSDM5260000

Related Products

Replaced byUC148, 6-Hydroxychlorzoxazone

References

referencePeter, et al., Hydroxylation of chlorzoxazone as a speciric probe for human liver cytochrome P450IIE1. Chem. Res. Toxicol. 3, 566-573, (1990)
 Twele, et al., Identification of chlorzoxazone metabolites in human urine. Arzneimittelforschung 32, 759, (1982)